Genetic studies overwhelmingly are based on data from people of European descent. But University of Maryland, Baltimore scientists are working to change that.

Researchers have developed the Genetics of Latin American Diversity database, pulling information from more than 200 genetic studies on almost 54,000 people of Hispanic and Latin descent.

Timothy O'Connor, associate professor at the University of Maryland at Baltimore School of Medicine Institute for Genome Sciences, said the diversity is important because 95% of participants in genetic studies come from northwestern Europe.

"What ends up happening as a result of that is, we have a restricted view of genetic variation that we see in the world," said O'Connor. "Because of that, we miss out on genetic variation that might be causing a disease in one population, but not in another population."

Even though Latino representation makes up less than 1% of genetic data, O'Connor added that the number of people in datasets is exploding.

He said that made it possible to gather so much genetic data on this population.

The University of Maryland database should save other researchers time and money they'd be using to collect this information on their own.

O'Connor said he believes the creation of this database moves past large categorizations in ancestry that are largely based on race.

"What this allows us to do is to say, 'No these are distant cousins. These are people that are closely related at a much more fine scale,'" said O'Connor. "It moves us from this thinking about groups as kind of separate, into starting to think of everybody as kind of a continuous ancestry."

The Census Bureau says more than 19% of Americans identify as Latino, including more than 12% of Marylanders.




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A new State of the Commonwealth report by Old Dominion University finds Virginia had a strong year in 2024. But researchers say challenges remain.

The report finds housing will be a major issue in the state, as local governments work to address housing shortages and zoning laws.

Virginia had its fourth straight year of economic growth in 2024, ranking as the number one state to do business.

Bob McNab, professor of economics at Old Dominion University, said the overall outlook for Virginia in 2025 is positive. But he said a number of factors may impact that forecast.

"We saw inflation decelerate, real wages - that's wages after inflation - rise, jobs continue to increase," said McNab. "As Virginia enters 2025, it is in a good position to continue growth."

McNab did warn that international trade, immigration, and the status of the federal workforce could impact Virginia's economy.

Despite data that points to a strong economy, consumers aren't quick to agree.

The report finds consumers still feel less optimistic about the state of the economy than before the COVID-19 pandemic.

Higher prices on goods and services because of inflation have driven that sentiment. McNab said people interact with prices daily - and their paycheck may be once or twice a month.

That, he said, leads to the data not coinciding with consumer feelings on the economy.

"And since 2019, real hourly earnings have increased after accounting for inflation," said McNab. "People's wages have outgained inflation. But they don't feel like that has occurred because they see prices much more frequently."

The report also finds Virginia's unemployment rate is nearing record lows.




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As the popular role-playing game Dungeons and Dragons turns 50, one Colorado State University instructor suggests today's political leaders could learn a lot by rolling the dice.

James Fielder, instructor and researcher of ludology (the study of games and gameplay) at Colorado State University, calls the game a master class in political strategy, covering everything from diplomacy to alliance forming to conflict resolution.

Fielder said players have to work together to achieve a goal. If you're at odds with each other, you don't achieve anything.

"The lesson is that we're learning to negotiate in order to overcome a challenge," Fielder explained. "That lesson sticks. You come out of the table, 'Oh, I learned how to negotiate with other people, and we overcame a challenge.' It worked."

A former Air Force lieutenant colonel, Fielder has more than two decades of experience designing war games and training exercises. He stressed role-playing is not just child's play. He compared the games to a ritual performance. When players are inside a game space -- which could be a football field, a card table, or a war room -- everything inside the game is very real, including wins, losses and lessons learned about the use of power.

Fielder added when a Dungeon Master reveals an unintended consequence of the players' decisions -- for example, the massacre of an entire town -- they frequently look at each other like, "What did we just do?"

"You will also find players who will play evil characters, who carry out atrocities in the game," Fielder observed. "But then when they come out, they don't feel good about themselves. They feel unclean, like, 'Oh my God, I can't believe I just did that.' And so, yes, that sends a very powerful message."

Fielder said even in today's modern age, games can be similar to an animist rite of passage, where participants believe a spiritual leader wearing an animal's skin is an actual god or animal.

"If you're wearing a suit to go to work, you're wearing the 'skin' of a businessperson," Fielder pointed out. "I was in the military for 25 years putting on the uniform, and wearing the 'skin' of a sergeant or a lieutenant colonel."

This story is based on original reporting by Stacy Nick for Colorado State University.

Ohio is leading the way in new research that may help those affected by lymphedema.

Lymphedema is a chronic condition that causes painful swelling due to buildup of fluid in the lymphatic system, which is part of a person's immune system. For many patients, this condition can develop following cancer treatment.

Teresa Lau, a breast cancer survivor and lymphedema patient at The Ohio State University James Cancer Center, described how new monitoring technology has provided her peace of mind.

"This is great for somebody who lives an hour away from OSU," she said. "It lets you know if, like, my arms swell up and so, what can I do? What are the next steps?"

The study Teresa referred to, called Project Limb Rescue, uses wearable technology to monitor lymphedema in real time. Ohioans with this condition can participate by visiting OSU for a brief session where they wear sensors that measure fluid buildup. The program aims to help patients detect swelling sooner, potentially reducing complications.

Lymphedema affects about four in 10 breast cancer survivors.

Study coordinator Lynne Brophy, a breast oncology clinical nurse specialist at the Ohio State Comprehensive Cancer Center, noted the benefits of the program for patients across Ohio.

"Our research study is to help people developing lymphedema detect it at home," she said. "It means they're saving money by not having as many physician visits."

Brophy added that research leads to new discoveries and encourages people to join the trial.

"I hope people will be open to participating and helping either themselves, perhaps, or their neighbor," she said.

OSU researchers are recruiting participants between ages 18 and 90 who have undergone lymph node removal surgery.